Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Reirradiation of head and neck cancer focusing on hypofractionated stereotactic body radiation therapy. | Yamazaki et al. Radiation Oncology 2011 6 98 http content 6 1 98 RADIATION ONCOLOGY REVIEW Open Access Reirradiation of head and neck cancer focusing on hypofractionated stereotactic body radiation therapy I_I I u XX -X -X x-zx -X 7 -X Iz I 1 2I I -X fx I X I r X V X u -XX X I 1 2 I I 1 -i f X rs - I 4-X 2 If X X z x Z X c -X T 4 -X X X u If z X X f X I_I I xvx X I 5 Hideya Yamazaki iNaoniro Kodani MIKIQ Ogita Kengo Sato and Kengo Himei Abstract Reirradiation Is a feasible option for patients who do not otherwise have treatment options available. Depending on the location and extent of the tumor reirradiation may be accomplished with external beam radiotherapy brachytherapy radiosurgery or Intensity modulated radiation therapy IMRT . Although there has been limited experience with hypofractionated stereotactic radiotherapy hSRT It may have the potential for curative or palliative treatment due to Its advanced precision technology particularly for limited small lesion. On the other hand severe late adverse reactions are anticipated with reIrradiation than with initial radiation therapy. The risk of severe late complications has been reported to be 20- 40 and Is related to prior radiotherapy dose primary site retreatment radiotherapy dose treatment volume and technique. Early researchers have observed lethal bleeding In such patients up to a rate of 14 . Recently similar rate of 10-15 was observed for fatal bleeding with use of modern hSRT like In case of carotid blowout syndrome. To determine the feasibility and efficacy of reIrradiation using modern technology we reviewed the pertinent literature. The potentially lethal side effects should be Kept In mind when reIrradiation by hSRT Is considered for treatment and efforts should be made to minimize the risk In any future investigations. Keywords Head Neck cancer reIrradiation Stereotactic radiotherapy Bleeding Introduction Locoregional failure is the predominant pattern of treatment failure and .
