Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài:"Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy. | Radiation Oncology BioMed Central Research Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy Hans Paul van der Laan Wil V Dolsma John H Maduro Erik W Korevaar and Johannes A Langendijk Address Department of Radiation Oncology University Medical Center Groningen University of Groningen Hanzeplein 1 9700 RB Groningen The Netherlands Email Hans Paul van der Laan - Wil V Dolsma - John H Maduro - Erik W Korevaar - Johannes A Langendijk - Corresponding author Open Access Published 31 January 2008 Received 22 October 2007 Radiation Oncology 2008 3 6 doi 1748-7I7X-3-6 Accepted 31 January 2008 This article is available from http content 3 1 6 2008 van der Laan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The shift from conventional two-dimensional 2D to three-dimensional 3D -conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this study was to compare coverage of computed tomography CT -based breast and boost planning target volumes PTV absolute volumes irradiated and dose delivered to the organs at risk with conventional 2D and 3D-conformal breast conserving radiotherapy. Methods Twenty-five patients with left-sided breast cancer were subject of CT-guided target definition and 3D-conformal dose-planning and conventionally defined target volumes and treatment plans were reconstructed on the planning CT. Accumulated dose-distributions were calculated for the conventional and 3D-conformal dose-plans
