Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer. | BioMed Central Radiation Oncology Research Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer Erik P Sulman Ritsuko Komaki Ann H Klopp James D Cox and Joe Y Chang Open Access Address Department of Radiation Oncology the University of Texas M. D. Anderson Cancer Center 1515 Holcombe Boulevard Houston TX USA Email Erik P Sulman - epsulman@ Ritsuko Komaki - rkomaki@ Ann H Klopp - aklopp@ James D Cox - jcox@ Joe Y Chang - jychang@ Corresponding author Published 30 January 2009 Received 19 November 2008 Accepted 30 January 2009 Radiation Oncology 2009 4 5 doi l748-7I7X-4-5 This article is available from http content 4 1 5 2009 Sulman et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Controversy still exists regarding the long-term outcome of patients whose uninvolved lymph node stations are not prophylactically irradiated for non-small cell lung cancer NSCLC treated with definitive radiotherapy. To determine the frequency of elective nodal failure ENF and in-field failure IFF we examined a large cohort of patients with NSCLC staged with positron emission tomography PET computed tomography CT and treated with 3-dimensional conformal radiotherapy 3D-CRT that excluded uninvolved lymph node stations. Methods We retrospectively reviewed the records of 115 patients with non-small cell lung cancer treated at our institution with definitive radiation therapy with or without concurrent chemotherapy CHT . All patients were treated with 3D-CRT including nodal regions determined by CT or PET to be disease involved. Concurrent platinum-based CHT was .
