Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Self-assessed bowel toxicity after external beam radiotherapy for prostate cancer - predictive factors on irritative symptoms, incontinence and rectal bleeding. | Radiation Oncology BioMed Central Research Self-assessed bowel toxicity after external beam radiotherapy for prostate cancer - predictive factors on irritative symptoms incontinence and rectal bleeding Michael Pinkawa Marc D Piroth Karin Fischedick Sandra Nussen Jens Klotz Richard Holy and Michael J Eble Address Department of Radiation Oncology RWTH Aachen University Pauwelsstrasse 30 52072 Aachen Germany Email Michael Pinkawa - mpinkawa@ Marc D Piroth - mpiroth@ Karin Fischedick - kfischedick@ Sandra Nussen - snussen@ Jens Klotz - jklotz@ Richard Holy-rholy@ Michael J Eble - meble@ Corresponding author Open Access Published 21 September 2009 Received 13 July 2009 Accepted 21 September 2009 Radiation Oncology 2009 4 36 doi 1748-717X-4-36 This article is available from http content 4 1 36 2009 Pinkawa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The aim of the study was to evaluate self-assessed bowel toxicity after radiotherapy RT for prostate cancer. In contrast to rectal bleeding information concerning irritative symptoms rectal urgency pain and incontinence after RT has not been adequately documented and reported in the past. Methods Patients n 286 have been surveyed prospectively before A at the last day Gy B a median time of two C and 16 months after RT D using a validated questionnaire Expanded Prostate Cancer Index Composite . Bowel domain score changes were analyzed and patient- dose-volume-related factors tested for a predictive value on three separate factors subscales irritative symptoms incontinence and rectal bleeding. Results Irritative symptoms were most strongly .
