Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis. | Available online http content 9 2 R27 Research article A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis Pierre-Antoine Gourraud1 Philippe Dieudé2 Jean-Frédéric Boyer3 4 Leonor Nogueira5 Anne Cambon-Thomsen7 Bernard Mazieres3 4 Frangois Cornélis6 Guy Serre5 Alain Cantagrel3 4 and Arnaud Constantin1 3 4 Service d Epidémiologie CHU Toulouse INSERM U558 Université Paul Sabatier Toulouse III Faculté de Médecine 37 allées Jules Guesde Toulouse Cedex 7 31073 France 2Service de Rhumatologie CHU Bichat Claude-Bernard 46 rue Henri Huchard Paris 75018 France 3GRCB40 UFR Sciences Médicales Rangueil 1 avenue du Professeur Jean Poulhès Toulouse Cedex 9 31 059 France 4Service de Rhumatologie CHU Toulouse Rangueil 1 avenue du Professeur Jean Poulhès Toulouse Cedex 9 31 059 France 5Laboratoire de Biologie Cellulaire et Cytologie CHU Toulouse Purpan Place du Docteur Baylac Toulouse cedex 9 31059 France 6GenHotel Genopole 2 rue Gaston Crémieux Evry Cedex 91 057 France 7INSERM U558 Faculté de Médecine 37 allées Jules Guesde Toulouse Cedex 7 31073 France Corresponding author Arnaud Constantin constant@ Received 27 Nov 2006 Revisions requested 2 Feb 2007 Revisions received 5 Mar 2007 Accepted 12 Mar 2007 Published 12 Mar 2007 Arthritis Research Therapy 2007 9 R27 doi ar2131 This article is online at http content 9 2 R27 2007 Gourraud et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract The HLA-DRB1 gene was reported to be associated with anticitrullinated protein peptide autoantibody ACPA production in rheumatoid arthritis RA patients. A new classification of HLA-DRB1 .
