Báo cáo y học: "Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. | Available online http content 9 4 R64 Research article Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants elevation of prostaglandin D2 levels Sung Mun Jung1 3-5 H Ralph Schumacher1 3 Hocheol Kim5 Miyeon Kim5 Seoung Hoon Lee2 and Frank Pessler4 Division of Rheumatology University of Pennsylvania 3600 Spruce St Philadelphia PA 19104 USA 2Department of Pathology and Laboratory Medicine 3400 Spruce St University of Pennsylvania Philadelphia PA 19104 USA 3Division of Rheumatology Veteran Affairs Medical Center University and Woodland Avenues Philadelphia PA 19104 USA 4Division of Rheumatology The Children s Hospital of Philadelphia 3405 Civic Center Blvd Philadelphia PA 19104 USA 5Faculty of Oriental Medicine Department of Herbal Pharmacology Kyung Hee University College of Oriental Medicine 1 Hoekidong Dongdaemoonku Seoul 130-701 Korea Corresponding author Frank Pessler pessler@ Received 5 Feb 2007 Revisions requested 26 Feb 2007 Revisions received 18 Apr 2007 Accepted 5 Jul 2007 Published 5 Jul 2007 Arthritis Research Therapy 2007 9 R64 doi ar2222 This article is online at http content 9 4 R64 2007 Jung et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Dried roots of the plants Acanthopanax senticosus Angelica sinensis and Scutellaria baicalensis are used in traditional oriental medicine and reportedly possess anti-inflammatory properties. Using the murine air pouch model of inflammation we investigated the efficacy and mode of action of an extract from these three plants in crystal-induced inflammation. Air pouches were raised on the backs of 8-week-old BALB c mice. Mice were

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