Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes. | Available online http content 9 4 R78 Research article Heterogeneity of autoantibodies in 100 patients with autoimmune myositis insights into clinical features and outcomes Martial Koenig1 Marvin J Fritzler2 Ira N Targoff3 Yves Troyanov1 and Jean-Luc Senécal1 University of Montreal School of Medicine and Laboratory for Research in Autoimmunity Centre Hospitalier de l Université de Montréal M-4243 1560 East Sherbrooke Street Montreal Quebec Canada H2L 4M1 2Faculty of Medicine HRB409 University of Calgary 3330 Hospital Dr. NW Calgary Alberta Canada T2N 4N1 3Arthritis and Immunology University of Oklahoma Health Sciences Center 825 NE 13th Street Oklahoma City OK 73104 and Oklahoma Medical Research Foundation Oklahoma City Oklahoma USA Corresponding author Jean-Luc Senécal Received 22 May 2007 Revisions requested 4 Jul 2007 Revisions received 28 Jul 2007 Accepted 9 Aug 2007 Published 9 Aug 2007 Arthritis Research Therapy 2007 9 R78 doi ar2276 This article is online at http content 9 4 R78 2007 Koenig et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract The objective of this study was to determine the prevalence mutual associations clinical manifestations and diagnoses associated with serum autoantibodies as detected using recently available immunoassays in patients with autoimmune myositis AIM . Sera and clinical data were collected from 100 patients with AIM followed longitudinally. Sera were screened cross-sectionally for 21 autoantibodies by multiplex addressable laser bead immunoassay line blot immunoassay immunoprecipitation of in vitro translated recombinant protein protein A assisted immunoprecipitation and .
