Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Seroprevalence of parvovirus B19 IgG in children affected by juvenile idiopathic arthritis. | Available online http content 9 4 R82 Research article Seroprevalence of parvovirus B19 IgG in children affected by juvenile idiopathic arthritis Benedikt Weissbrich1 Yvonne SuB-Frohlich1 2 and Hermann J Girschick2 Open Access institute of Virology and Immunobiology University of Wurzburg Versbacher Str 7 97078 Wurzburg Germany 2Section of Paediatric Rheumatology Immunology and Infectious diseases Children s Hospital University of Wurzburg Josef-Schneider-Str 2 97080 Wurzburg Germany Corresponding author Benedikt Weissbrich weissbrich@ Received 25 May 2007 Revisions requested 19 Jul 2007 Revisions received 29 Jul 2007 Accepted 30 Aug 2007 Published 30 Aug 2007 Arthritis Research Therapy 2007 9 R82 doi ar2281 This article is online at http content 9 4 R82 2007 Weissbrich et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Parvovirus PV B19 is the causative agent of the childhood disease erythema infectiosum. An association of PV B19 with chronic arthropathies sometimes resembling rheumatoid arthritis or juvenile idiopathic arthritis JIA has repeatedly been described. Other studies however have failed to identify any such relationship. In order to study further whether there is a link between PV B19 and JIA we determined the prevalence of PV B19 specific IgG antibodies in serum samples from children with rheumatoid diseases and compared it with the prevalence in unaffected children We reasoned that if there is an association between PV B19 and JIA then the prevalence of PV B19 IgG in the children with JIA should be higher than in the control group. PV B19 IgG status was tested in 406 children with JIA and related diseases and in 146 children
