Báo cáo khoa học: " Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL. | Radiation Oncology BioMed Central Research Open Access Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL Sayako Oota 1 Hitoshi Shibuyat2 Ryo-ichi Yoshimurat2 Hiroshi Watanabet2 and Masahiko Miurat2 Address Department of Radiology Asahi General Hospital I-1326 Asahi Chiba Japan and 2Department of Radiology Tokyo Medical and Dental University 1-5-45 Yushima Bunkyo Tokyo Japan Email Sayako Oota - sayacoral@ Hitoshi Shibuya - Ryo-ichi Yoshimura - ysmrmrad@ Hiroshi Watanabe - Masahiko Miura - Corresponding author fEqual contributors Published 12 July 2006 Received 10 March 2006 Radiation Oncology 2006 1 21 doi 1748-717X-1-21 Accepted 12 July 2006 This article is available from http content 1 1 21 2006 Oota et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified treatment policy. Results Between 1970 and 1998 433 patients with stage II tongue squamous cell carcinoma were treated by low-dose-rate brachytherapy. This series included 277 patients treated with a linear source with a minimum follow-up of 3 years. A spacer was introduced in 1987. The primary local control rates were . Conclusion In the multivariate analysis an invasive growth pattern was a significant factor for local recurrence. The disease-related survival was influenced by old age and an invasive growth pattern. A spacer lowered mandibular bone complications. The growth pattern was the most

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