Báo cáo khoa học: " Enhanced radiation sensitivity and radiation recall dermatitis (RRD) after hypericin therapy – case report and review of literature"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Enhanced radiation sensitivity and radiation recall dermatitis (RRD) after hypericin therapy – case report and review of literature. | Radiation Oncology BioMed Central Open Access Short report Enhanced radiation sensitivity and radiation recall dermatitis RRD after hypericin therapy - case report and review of literature Kurt Putnik Peter Stadler Christof Schafer and Oliver Koelbl Address Department of Radiation Oncology University of Regensburg Josef-Strauss Allee 11 93053 Regensburg Germany Email Kurt Putnik - Peter Stadler - Christof Schafer - Oliver Koelbl - Corresponding author Published 01 September 2006 Received II May 2006 Accepted 01 September 2006 Radiation Oncology 2006 1 32 doi 1748-717X-1-32 This article is available from http content 1 1 32 2006 Putnik et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Modern radiotherapy RT reduces the side effects at organ at risk. However skin toxicity is still a major problem in many entities especially head and neck cancer. Some substances like chemotherapy provide a risk of increased side effects or can induce a recall phenomenon imitating acute RT-reactions months after RT. Moreover some phototoxic drugs seem to enhance side effects of radiotherapy while others do not. We report a case of radiation recall dermatitis RRD one year after RT as a result of taking hypericin St. John s wort . Case report A 65 year old man with completely resected squamous cell carcinoma of the epiglottis received an adjuvant locoregional RT up to a dose of Gy. The patient took hypericin during and months after RT without informing the

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