Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Reproducibility of target volumes generated using uncoached 4-dimensional CT scans for peripheral lung cancer. | Radiation Oncology BioMed Central Research Reproducibility of target volumes generated using uncoached 4-dimensional CT scans for peripheral lung cancer Ylanga G van der Geld Frank J Lagerwaard John R van Sõrnsen de Koste Johan P Cuijpers Ben J Slotman and Suresh Senan Open Access Address Department of Radiation Oncology VU University medical center Amsterdam The Netherlands Email Ylanga G van der Geld - Frank J Lagerwaard - John R van Sõrnsen de Koste - Johan P Cuijpers - Ben J Slotman - Suresh Senan - Corresponding author Published 01 November 2006 Received 19 September 2006 Accepted 01 November 2006 Radiation Oncology 2006 1 43 doi l748-7l 7X-I-43 This article is available from http content l l 43 2006 van der Geld et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background 4-dimensional CT 4DCT scans are increasingly used to account for mobility during radiotherapy planning. As variations in respiratory patterns can alter observed motion with consequent changes in the generated target volumes we evaluated the reproducibility of 4D target volumes generated during repeat uncoached quiet respiration. Methods A retrospective analysis was performed on two successive scans 4DCTl and 4DCT2 generated at the same scanning session for 26 patients with peripheral lung cancer treated with stereotactic radiotherapy SRT . The volume and position of planning target volumes PTV4DCTl and PTV4DCT2 contoured on both scans were compared and a dosimetric analysis performed. A SRT plan optimized for each PTV was sequentially applied to the other PTV and coverage by the 80 .
