Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " The influence of smoking and other risk factors on the outcome after radiochemotherapy for anal cancer. | Radiation Oncology BioMed Central Research Open Access The influence of smoking and other risk factors on the outcome after radiochemotherapy for anal cancer Sabine Kathrin Mai Grit Welzel Verena Haegele and Frederik Wenz Address Department of Radiation Oncology of the University Medical Center Mannheim Germany Email Sabine Kathrin Mai - Grit Welzel - Verena Haegele - verena_haegele@ Frederik Wenz - Corresponding author Published 21 August 2007 Received 31 May 2007 Radiation Oncology 2007 2 30 doi l748-7l 7X-2-30 Accepted 21 August 2007 This article is available from http content 2 l 30 2007 Mai et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Smoking is an important risk factor for the development of cancer. Smoking during radiochemotherapy therapy may have a negative influence on prognosis. We evaluated the effect of smoking during radiochemotherapy on the outcome for patients with anal cancer. Methods Sixty-eight patients 34 smokers 34 non-smokers treated by radiochemotherapy for anal cancer were analysed. The effect of smoking during radiochemotherapy and other risk factors gender T- and N category tumor site dose therapy protocol on disease-specific survival DSS local control LC and colostomy free survival CFS was evaluated. Results There was a significant difference in age and male female ratio between the two groups. With a median follow up of 22 months max. ll9 DSS LC and CFS were 88 84 and 84 . A significant difference in local control between smokers S and non-smokers NS was found S 74 vs. NS 94 p .03 . For DSS and CFS a difference in .
