Báo cáo khoa học: " Regional radiotherapy versus an axillary lymph node dissection after lumpectomy: a safe alternative for an axillary lymph node dissection in a clinically uninvolved axilla in breast cancer. A case control study with 10 years follow up"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Regional radiotherapy versus an axillary lymph node dissection after lumpectomy: a safe alternative for an axillary lymph node dissection in a clinically uninvolved axilla in breast cancer. A case control study with 10 years follow up. | Radiation Oncology BioMed Central Research Regional radiotherapy versus an axillary lymph node dissection after lumpectomy a safe alternative for an axillary lymph node dissection in a clinically uninvolved axilla in breast cancer. A case control study with 10 years follow up Patty H Spruit1 Sabine Siesling2 Marloes AG Elferink2 Ernest JA Vonk1 and Carel JM Hoekstra 1 Open Access Address 1Radiotherapeutic Institute RISO Deventer The Netherlands and Comprehensive Cancer Centre Stedendriehoek Twente Enschede The Netherlands Email Patty H Spruit - Sabine Siesling - Marloes AG Elferink - Ernest JA Vonk - Carel JM Hoekstra - Corresponding author Published 30 October 2007 Received 19 June 2007 Radiation Oncology 2007 2 40 doi 1748-717X-2-40 Accepted 30 October 2007 This article is available from http content 2 1 40 2007 Spruit et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The standard treatment of the axilla in breast cancer used to be an axillary lymph node dissection. An axillary lymph node dissection is known to give substantial risks of morbidity. In recent years the sentinel node biopsy has become common practice. Future randomized study results will determine whether the expected decrease in morbidity can be proven. Methods Before the introduction of the sentinel node biopsy we conducted a study in which 180 women of 50 years and older with T1 T2 cN0 breast cancer were treated with breast conserving therapy. Instead of an axillary lymph node dissection regional radiotherapy was given in combination with tamoxifen RT-group . The study group was compared with 341 patients

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