Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. | Available online http content 10 2 R43 Research article Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis Denise Richardson1 Richard G Pearson2 Nisha Kurian3 M Liaque Latif3 Michael J Garle3 David A Barrett1 David A Kendall3 Brigitte E Scammell2 Alison J Reeve4 and Victoria Chapman3 1Centre for Analytical Bioscience School of Pharmacy University of Nottingham Nottingham NG7 2RD UK 2Division of Orthopaedic and Accident Surgery School of Medical Surgical Sciences University of Nottingham Queen s Medical Centre Campus Nottingham NG7 2UH UK 3School of Biomedical Sciences University of Nottingham Nottingham NG7 2UH UK 4Neurology Centre of Excellence for Drug Discovery GlaxoSmithKline Pharmaceuticals 3rd Avenue Harlow Essex CM19 5AW UK Contributed equally Corresponding author Victoria Chapman Received 18 Sep 2007 Revisions requested 13 Dec 2007 Revisions received 6 Mar 2008 Accepted 16 Apr 2008 Published 16 Apr 2008 Arthritis Research Therapy 2008 10 R43 doi ar2401 This article is online at http content 10 2 R43 2008 Richardson et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Cannabis-based medicines have a number of therapeutic indications including anti-inflammatory and analgesic effects. The endocannabinoid receptor system including the cannabinoid receptor 1 CB1 and receptor 2 CB2 and the endocannabinoids are implicated in a wide range of physiological and pathophysiological processes. Pre-clinical and clinical studies have demonstrated that cannabis-based drugs have therapeutic potential in inflammatory diseases
