Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project. | Available online http content 10 4 R75 Research article Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis the Swedish TIRA project Anna Svard1 2 Alf Kastbom2 Ảsa Reckner-Olsson2 and Thomas Skogh2 Rheumatology Clinic Falu Hospital SE-791 82 Falun Sweden 2AIR Rheumatology Unit Department of Clinical and Experimental Medicne Faculty of Health Sciences Linkoping University Hospital SE-581 85 Linkoping Sweden Corresponding author Anna Svard Received 31 Mar 2008 Revisions requested 13 May 2008 Revisions received 9 Jun 2008 Accepted 4 Jul 2008 Published 4 Jul 2008 Arthritis Research Therapy 2008 10 R75 doi ar2449 This article is online at http content 10 4 R75 2008 Svard et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The present study was carried out to assess whether IgA-class antibodies against eyelie citrullinated peptides IgA anti-CCP in recent-onset rheumatoid arthritis add diagnostic and or prognostic information to IgG anti-CCP analysis. Methods Serum samples were obtained from 228 patients with recent-onset 12 months rheumatoid arthritis at the time of inclusion in the Swedish TIRA cohort Swedish Early Intervention in Rheumatoid Arthritis . Sera from 72 of these patients were also available at the 3-year follow-up. Disease activity and functional ability measures erythrocyte sedimentation rate serum C-reactive protein 28-joint count Disease Activity Score physician s assessment of disease activity and the Swedish version of the Health Assessment Questionnaire were registered at inclusion and at regular follow-ups during 3 years. An IgA anti-CCP .
