Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Fibromyalgia and sleep-disordered breathing: the missing link. | Available online http content 10 6 408 Letter Fibromyalgia and sleep-disordered breathing the missing link Denis Martinez and Cristiane Maria Cassol Division of Cardiology Hospital de Clinicas de Porto Alegre Universidade Federal do Rio Grande do Sul Rua Ramiro Barcelos 2350 - Porto Alegre RS - Brazil - 90035-903 Corresponding author Cristiane Maria Cassol ccassol@ Published 25 November 2008 Arthritis Research Therapy 2008 10 408 doi ar2538 This article is online at http content 10 6 408 2008 BioMed Central Ltd See related review articles by Martinez-Lavin http content 9 4 216 and Staud http content 8 3 208 related research article by Vargas-Alarcón http content 9 5 R110 related editorial by Eisinger http content 9 4 105 related letter by Felix and Fontenele http content 9 5 404 and related response by Eisinger http content 10 6 409 Recently Martinez-Lavin 1 proposed a model of sympathetically maintained neuropathic pain syndrome that has the merit of scrutinizing possible mechanisms behind the central sensitization model 2 . Eisinger 3 in an editorial comment raises the issue of heterogeneity permeating Martinez-Lavin s proposition. Since it is difficult to establish a traumatic trigger event in all cases Eisinger considers multicausality as more reasonable than a single post-traumatic etiology for all cases. Felix and Fontenele 4 further explored this venue speculating that the orthostatic intolerance symptoms seen in the majority of fibromyalgia patients are a consequence of sympathetic hyperactivity. The idea that a COMT val-158-met polymorphism may cause higher cathecolamine levels has been explored 5 . Loevinger and colleagues 6 have shown that the metabolic syndrome is more common in individuals with fibromyalgia who also have higher body mass index blood .