Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study. | Available online http content 10 6 R145 Research article Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis a cross-sectional study Tracey E Toms1 2 Vasileios F Panoulas1 Karen MJ Douglas1 Helen R Griffiths3 and George D Kitas1 2 Department of Rheumatology Dudley Group of Hospitals NHS Trust Russells Hall Hospital Dudley West Midlands DY1 2HQ UK 2Arthritis Research Campaign Epidemiology Unit Manchester University Oxford Road Manchester M13 9PL UK 3Life and Health Sciences Aston University Aston Triangle Birmingham West Midlands B4 7ET UK Corresponding author George D Kitas Received 2 Oct 2008 Revisions requested 31 Oct 2008 Revisions received 23 Nov 2008 Accepted 17 Dec 2008 Published 17 Dec 2008 Arthritis Research Therapy 2008 10 R145 doi ar2578 This article is online at http content 10 6 R145 2008 Toms et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Rheumatoid arthritis RA associates with excessive cardiovascular morbidity and mortality attributed to both traditional and novel cardiovascular risk factors. The metabolic syndrome a cluster of classical cardiovascular risk factors including hypertension obesity glucose intolerance and dyslipidaemia is highly prevalent in RA. Reports suggest that long-term glucocorticoid GC use may exacerbate individual cardiovascular risk factors but there have been no studies in RA to assess whether it associates with the metabolic syndrome. We examined whether GC exposure associates with the presence of metabolic syndrome in patients with RA. Methods RA patients n 398 with detailed clinical and .

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