Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Enhanced reactivity to pain in patients with rheumatoid arthritis. | Available online http content 11 3 R61 Research article Enhanced reactivity to pain in patients with rheumatoid arthritis Robert R Edwards1 2 Ajay D Wasan1 Clifton O Bingham III3 Joan Bathon3 Jennifer A Haythornthwaite2 Michael T Smith2 and Gayle G Page4 Department of Anesthesiology Harvard Medical School Brigham Women s Hospital 850 Boylston Street Suite 302 Chestnut Hill MA 02467 USA __ 2Department of Psychiatry Johns Hopkins University School of Medicine 600 N. Wolfe Street Baltimore MD 21 287 USA 3Division of Rheumatology Johns Hopkins University School of Medicine 5200 Eastern Avenue MFL Suite 41 00 Baltimore MD 21224 USA 4Johns Hopkins University School of Nursing 525 N. Wolfe Street Baltimore MD 21287 USA Corresponding author Robert R Edwards RREdwards@ Received 16 Feb 2009 Revisions requested 1 Apr 2009 Revisions received 17 Apr 2009 Accepted 4 May 2009 Published 4 May 2009 Arthritis Research Therapy 2009 11 R61 doi ar2684 This article is online at http content 11 3 R61 2009 Edwards et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Maladaptive physiological responses to stress appear to play a role in chronic inflammatory diseases such as rheumatoid arthritis RA . However relatively little stress research in RA patients has involved the study of pain the most commonly reported and most impairing stressor in RA. In the present study we compared psychophysical and physiological responses to standardized noxious stimulation in 19 RA patients and 21 healthy controls. Methods Participants underwent a single psychophysical testing session in which responses to a variety of painful stimuli were recorded and blood .
