Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis. | Available online http content 11 5 R135 Research article Diagnostic and prognostic value of antibodies against chimeric fibrin filaggrin citrullinated synthetic peptides in rheumatoid arthritis Raimon Sanmartí1 Eduard Graell2 Maria L Perez3 Guadalupe Ercilla4 Odette Vinas4 Jose A Gomez-Puerta1 Jordi Gratacós2 Alejandro Balsa5 Maria J Gómara3 Marta Larrosa2 Juan D Canete1 and Isabel Haro3 Open Access Rheumatology Service Hospital Clinic of Barcelona IDIBAPS Villarroel 170 08036 Barcelona Spain 2Rheumatology Unit Hospital Universitari Parc Tauli of Sabadell Parc Tauli s n 08208 Sabadell Barcelona Spain 3Unit of Synthesis and Biomedical Applications of Peptides IQAC-CSIC Jordi Girona 1 8-26 08034 Barcelona Spain 4Immunology Service Hospital Clinic of Barcelona Villarroel 170 08036 Barcelona Spain 5Rheumatology Service Hospital Universitario La Paz Paseo de la Castellana 261 28046 Madrid Spain Corresponding author Raimon Sanmarti sanmarti@ Received 29 Apr 2009 Revisions requested 13 May 2009 Revisions received 14 Aug 2009 Accepted 2 Sep 2009 Published 2 Sep 2009 Arthritis Research Therapy 2009 11 R135 doi 86 ar2802 This article is online at http content 11 5 R135 2009 Sanmarti et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Evidence suggests that citrullinated fibrin ogen may be a potential in vivo target of anticitrullinated protein peptide antibodies ACPA in rheumatoid arthritis RA . We compared the diagnostic yield of three enzyme-linked immunosorbent assay ELISA tests by using chimeric fibrin filaggrin citrullinated synthetic peptides CFFCP1 CFFCP2 CFFCP3 with a commercial CCP2-based test in RA and analyzed their prognostic values .
