Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The prognostic value of baseline erosions in undifferentiated arthritis. | Available online http content 11 5 R155 Research article The prognostic value of baseline erosions in undifferentiated arthritis Mohamed M Thabet1 2 Thomas WJ Huizinga1 Désirée M van der Heijde1 and Annette HM van der Helm-van Mil1 Department of Rheumatology Leiden University Medical Center Albinusdreef 2 Leiden PO Box 9600 2300RC The Netherlands 2Department of Internal Medicine Assiut University Hospital University Street 1 Assiut . Box 71515 Egypt Corresponding author Mohamed M Thabet Received 5 Aug 2009 Revisions requested 28 Aug 2009 Revisions received 21 Sep 2009 Accepted 15 Oct 2009 Published 15 Oct 2009 Arthritis Research Therapy 2009 11 R155 doi 86 ar2832 This article is online at http content 11 5 R155 2009 Thabet et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Undifferentiated arthritis UA has a variable disease course 40 to 50 of UA patients remit spontaneously while 30 develop rheumatoid arthritis RA . Identifying the UA patients who will develop RA is essential to initiate early disease-modifying anti-rheumatic drug DMARD therapy. Although the presence of bone erosions at baseline is predictive for a severe destructive disease course in RA the prognostic importance of erosive joints for disease outcome in UA is unknown. This study evaluates the predictive value of erosive joints for the disease outcome in UA as measured by RA development and disease persistency. Methods Baseline hands and feet radiographs of 518 UA patients were evaluated for erosions using a clinical definition as well as the Sharp van der Heijde method. After 1 year follow-up patients were re-assessed for the fulfilment of the 1987
