Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study. | Available online http content 11 5 R160 Research article The relationship between disease activity sleep psychiatric distress and pain sensitivity in rheumatoid arthritis a cross-sectional study Yvonne C Lee1 Lori B Chibnik1 Bing Lu1 Ajay D Wasan2 Robert R Edwards2 Anne H Fossel1 Simon M Helfgott1 Daniel H Solomon1 Daniel J Clauw3 and Elizabeth W Karlson1 Division of Rheumatology Immunology and Allergy Brigham and Women s Hospital 75 Francis Street PBB-B3 Boston MA 02115 USA 2Pain Management Center Brigham and Women s Hospital 850 Boylston Street Chestnut Hill MA 02467 USA 3Chronic Pain and Fatigue Center University of Michigan Medical School Domino s Farms Lobby M PO Box 385 24 Frank Lloyd Wright Drive Ann Arbor MI 48106 USA Corresponding author Yvonne C Lee ylee9@ Received 14 Jul 2009 Revisions requested 27 Aug 2009 Revisions received 23 Sep 2009 Accepted 29 Oct 2009 Published 29 Oct 2009 Arthritis Research Therapy 2009 11 R160 doi 86 ar2842 This article is online at http content 11 5 R160 2009 Lee et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Despite recent advances in anti-inflammatory therapy rheumatoid arthritis RA patients continue to rate pain as a priority. The etiology of RA pain is likely multifactorial including both inflammatory and non-inflammatory components. In this study we examine the association between disease activity sleep psychiatric distress and pain sensitivity in RA. Methods Fifty-nine female RA patients completed questionnaires and underwent pressure pain threshold testing to assess hyperalgesia allodynia at joint and non-joint sites. Blood samples were taken to measure C-reactive protein CRP
