Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study. | Giardino et al. Respiratory Research 2010 11 29 http content 11 1 29 RESPIRATORY RESEARCH RESEARCH Open Access Anxiety is associated with diminished exercise performance and quality of life in severe emphysema a cross-sectional study Nicholas D Giardino1 3 Jeffrey L Curtis2 4 Adin-Cristian Andrei2 Vincent S Fan5 Joshua O Benditt5 Mark Lyubkin1 3 6 l T-x8 r2 10 Keith Naunheim Gerard Criner Barry Make Robert A Wise Susan K Murray Alfred P Fishman Frank C Sciurba11 Israel Liberzon1 3 Fernando J Martinez2 the NETT Research Group Abstract Background Anxiety in patients with chronic obstructive pulmonary disease COPD is associated with selfreported disability. The purpose of this study is to determine whether there is an association between anxiety and functional measures quality of life and dyspnea. Methods Data from 1828 patients with moderate to severe emphysema enrolled in the National Emphysema Treatment Trial NETT collected prior to rehabilitation and randomization were used in linear regression models to test the association between anxiety symptoms measured by the Spielberger State Trait Anxiety Inventory STAI and a six-minute walk distance test 6 MWD b cycle ergometry peak workload c St. Georges Respiratory Questionnaire SRGQ and d UCSD Shortness of Breath Questionnaire SOBQ after controlling for potential confounders including age gender FEV1 predicted DLCO predicted and the Beck Depression Inventory BDI . Results Anxiety was significantly associated with worse functional capacity 6 MWD B p .001 ergometry peak workload B p .04 quality of life B .172 p .001 and shortness of breath B .180 p .001 . Regression coefficients show that a 10 point increase in anxiety score is associated with a mean decrease in 6 MWD of 9 meters a 1 Watt decrease in peak exercise workload and an increase of almost 2 points on both the SGRQ and SOBQ. Conclusion In clinically stable patients with moderate to severe emphysema anxiety is associated with
