Báo cáo y học: " Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients. | Available online http content 11 6 R179 Research article Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state results from a cohort of 21 patients Caroline Charpin1 Sandrine Guis1 Philippe Colson2 3 Patrick Borentain4 Jean-Pierre Mattéi1 Patrice Alcaraz1 Nathalie Balandraud1 Benoit Thomachot1 Jean Roudier1 and René Gérolami4 Open Access Service de Rhumatologie Centre Hospitalier Universitaire Conception 147 Boulevard Baille 13385 Marseille France 2Laboratoire de Virologie Fédération Hospitalière de Microbiologie Clinique Centre Hospitalo-Universitaire Timone 264 Rue Saint-Pierre 13385 Marseille France 3URMITE CNRS-IRD UMR 6236 Facultés de Médecine et de Pharmacie Université de la Méditerranée 27 Boulevard Jean Moulin 13385 Marseille France 4Service d Hépato-gastroentérologie Centre Hospitalier Universitaire Conception 147 Boulevard Baille 13385 Marseille France Contributed equally Corresponding author Sandrine Guis Received 7 Jun 2009 Revisions requested 20 Aug 2009 Revisions received 18 Sep 2009 Accepted 26 Nov 2009 Published 26 Nov 2009 Arthritis Research Therapy 2009 11 R179 doi 86 ar2868 This article is online at http content 11 6 R179 2009 Charpin et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Reactivation of hepatitis B virus HBV infection in patients with past infection has been described in 5 to 10 of individuals undergoing immunosuppressive therapies. No data are available to date on the outcome of patients treated by tumour necrosis factor-alpha TNFa inhibitors for chronic arthritis with a serological pattern of past HBV infection. The aim of our study was to .

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