Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Poverty, dirt, infections and non-atopic wheezing in children from a Brazilian urban center. | Barreto et al. Respiratory Research 2010 11 167 http content 11 1 167 RESPIRATORY RESEARCH RESEARCH Open Access Poverty dirt infections and non-atopic wheezing in children from a Brazilian urban center 1 r- I- s I 2 3 1 3 1 Mauricio L Barreto Sergio S Cunha Rosemeire Fiaccone Renata Esquivel Leila D Amorim Sheila Alvim Matildes Prado 1 Alvaro A Cruz4 Philip J Cooper5 Darci N Santos1 Agostino Strina1 Neuza Alcantara-Neves6 Laura C Rodrigues7 Abstract Background The causation of asthma is poorly understood. Risk factors for atopic and non-atopic asthma may be different. This study aimed to analyze the associations between markers of poverty dirt and infections and wheezing in atopic and non-atopic children. Methods 1445 children were recruited from a population-based cohort in Salvador Brazil. Wheezing was assessed using the ISAAC questionnaire and atopy defined as allergen-specific IgE kU L. Relevant social factors environmental exposures and serological markers for childhood infections were investigated as risk factors using multivariate multinomial logistic regression. Results Common risk factors for wheezing in atopic and non-atopic children respectively were parental asthma and respiratory infection in early childhood. No other factor was associated with wheezing in atopic children. Factors associated with wheezing in non-atopics were low maternal educational level OR 95 CI low frequency of room cleaning OR 95 CI presence of rodents in the house OR 95 CI and day care attendance OR 95 CI . Conclusions Non-atopic wheezing was associated with risk factors indicative of poverty dirt and infections. Further research is required to more precisely define the mediating exposures and the mechanisms by which they may cause non-atopic wheeze. Background An estimated 300 million people have asthma worldwide the prevalence has increased over the past 40 years or so among children in .
