Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"A systematic review of the role of vitamin insufficiencies and supplementation in COPD. | Tsiligianni and van der Molen Respiratory Research 2010 11 171 http content 11 1 171 RESPIRATORY RESEARCH REVIEW Open Access A systematic review of the role of vitamin insufficiencies and supplementation in COPD Ioanna G Tsiligianni Thys van der Molen Abstract Background Pulmonary inflammation oxidants-antioxidants imbalance as well as innate and adaptive immunity have been proposed as playing a key role in the development of COPD. The role of vitamins as assessed either by food frequency questionnaires or measured in serum levels have been reported to improve pulmonary function reduce exacerbations and improve symptoms. Vitamin supplements have therefore been proposed to be a potentially useful additive to COPD therapy. Methods A systematic literature review was performed on the association of vitamins and COPD. The role of vitamin supplements in COPD was then evaluated. Conclusions The results of this review showed that various vitamins vitamin C D E A beta and alpha carotene are associated with improvement in features of COPD such as symptoms exacerbations and pulmonary function. High vitamin intake would probably reduce the annual decline of FEV1. There were no studies that showed benefit from vitamin supplementation in improved symptoms decreased hospitalization or pulmonary function. Introduction COPD in all stages of severity is a very prevalent disease and a great burden for patients and society 1 . In affluent countries COPD is related to smoking over a long period of time whereas in many other countries it is also related to indoor and outdoor air pollution 1 . The pathology of chronic obstructive pulmonary disease include pulmonary inflammation oxidants-antioxidants imbalance protease-antiprotease imbalance and both innate and adaptive immunity 2 3 . Smoking cessation has been proven to be effective in stopping further deterioration of pulmonary function reducing symptoms and improving overall health 4 . Smoking cessation however
