Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis. | Jones et al. Respiratory Research 2011 12 5 http content 12 1 5 RESPIRATORY RESEARCH RESEARCH Open Access Parental and household smoking and the increased risk of bronchitis bronchiolitis and other lower respiratory infections in infancy systematic review and meta-analysis 1 1 1 2 1 1 Laura L Jones Ahmed Hashim Tricia McKeever Derek G Cook John Britton Jo Leonardi-Bee Abstract Background Passive smoke exposure increases the risk of lower respiratory infection LRI in infants but the extensive literature on this association has not been systematically reviewed for nearly ten years. The aim of this paper is to provide an updated systematic review and meta-analysis of studies of the association between passive smoking and LRI and with diagnostic subcategories including bronchiolitis in infants aged two years and under. Methods We searched MEDLINE and EMBASE to November 2010 reference lists from publications and abstracts from major conference proceedings to identify all relevant publications. Random effect pooled odds ratios OR with 95 confidence intervals CI were estimated. Results We identified 60 studies suitable for inclusion in the meta-analysis. Smoking by either parent or other household members significantly increased the risk of LRI odds ratios OR were 95 CI to for paternal smoking 95 CI to if both parents smoked and 95 CI to for any household member smoking. Pre-natal maternal smoking OR 95 CI to had a weaker effect than post-natal smoking OR 95 CI to . The strongest effect was on bronchiolitis where the risk of any household smoking was increased by an OR of 95 CI to . Conclusions Passive smoking in the family home is a major influence on the risk of LRI in infants and especially on bronchiolitis. Risk is particularly strong in relation to post-natal maternal smoking. Strategies to prevent passive smoke exposure in young children are an urgent .
