Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Membrane diffusion- and capillary blood volume measurements are not useful as screening tools for pulmonary arterial hypertension in systemic sclerosis: a case control study. | Respiratory Research BioMed Central Research Membrane diffusion- and capillary blood volume measurements are not useful as screening tools for pulmonary arterial hypertension in systemic sclerosis a case control study Maria J Overbeek 1 Herman Groepenhoff1 Alexandre E Voskuyl2 Egbert F Smit1 Jochem WL Peeters3 Anton Vonk-Noordegraaf1 Marieke D Spreeuwenberg4 Ben C Dijkmans2 and Anco Boonstra1 Open Access Address Department of Pulmonary Diseases VU University Medical Center Amsterdam The Netherlands 2Department of Rheumatology VU University Medical Center Amsterdam The Netherlands 3Department of Radiology Groene Hart Hospital The Netherlands and 4Department of Clinical Epidemiology and Biostatistics VU University Medical Center The Netherlands Email Maria J Overbeek - Herman Groepenhoff - Alexandre E Voskuyl - Egbert F Smit - Jochem WL Peeters - Anton Vonk-Noordegraaf- Marieke D Spreeuwenberg - Ben C Dijkmans - Anco Boonstra - Corresponding author Published I October 2008 Received 8 May 2008 Respiratory Research 2008 9 68 doi 1465-9921 -9-68 Accepted 1 October 2008 This article is available from http content 9 1 68 2008 Overbeek et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background There is no optimal screening tool for the assessment of pulmonary arterial hypertension PAH in patients with systemic sclerosis SSc . A decreasing transfer factor of the lung for CO TLCO is associated with the development of PAH in SSc. TLCO can be partitioned into the diffusion of the alveolar capillary membrane Dm and