Báo cáo y học: " Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation. | Respiratory Research BioMed Central Open Access Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation Esmaeil Mortaz 1 2 Zsofia Lazar3 Leo Koenderman4 Aletta D Kraneveld1 Frans P Nijkamp1 and Gert Folkerts1 Address division of Pharmacology and Pathophysiology Utrecht Institute for Pharmaceutical Sciences Utrecht University Utrecht the Netherlands 2Department of Clinical Biochemistry Faculty of Medical Sciences Tarbiat Modares University Tehran Iran and Department of Basic Science Section of Biochemistry Faculty of Veterinary Medicine Urmia University Urmia Iran institute of Human Physiology and Clinical Experimental Research Semmelweis University 78 a Ulloi Str Budapest Hungary and 4Department of Respiratory Medicine University Medical Center Utrecht Utrecht the Netherlands Email Esmaeil Mortaz - emortaz@ Zsofia Lazar - Leo Koenderman - Aletta D Kraneveld - Frans P Nijkamp - Gert Folkerts - Corresponding author Published 10 June 2009 Received 6 October 2008 Respiratory Research 2009 10 47 doi l465-992l-l0-47 Accepted I0 June 2009 This article is available from http content l0 l 47 2009 Mortaz et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Myeloid and plasmacytoid dendritic cells mDCs pDC are crucial to the immune system detecting microorganisms and linking the innate and adaptive immunity. pDC are present in small quantities in tissues that are in contact with the external environment mainly the skin the inner lining of the nose lungs stomach and intestines. They .

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