Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" " Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro. | Respiratory Research BioMed Central Open Access Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro Xiao-Yun Fan1 2 3 Arjen van den Berg2 3 Mieke Snoek2 3 Laurens G van der Flier2 Barbara Smids2 3 Henk M Jansen2 Rong-Yu Liu 1 and René Lutter 2 3 Address Department of Pulmonology The Geriatric Institute of Anhui The First Affiliated Hospital of Anhui Medical University Hefei Anhui 230022 PR China 2Department of Pulmonology Academic Medical Centre University of Amsterdam Amsterdam the Netherlands and 3Department of Experimental Immunology Academic Medical Centre University of Amsterdam Amsterdam the Netherlands Email Xiao-Yun Fan - smallcloud670820@ Arjen van den Berg - arjenvandenberg@ Mieke Snoek - Laurens G van der Flier - Barbara Smids - Henk M Jansen - Rong-Yu Liu - anhuigi@ René Lutter - Corresponding authors Published 3 July 2009 Received 9 February 2009 Respiratory Research 2009 10 62 doi 1465-9921-10-62 Accepted 3 July 2009 This article is available from http content 10 1 62 2009 Fan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Previously we showed that reduced availability of the essential amino acid tryptophan per se attenuates post-transcriptional control of interleukin IL -6 and IL-8 leading to hyperresponsive production of these inflammatory mediators by airway epithelial cells. Availability of the non-essential amino acid arginine in the inflamed airway mucosa of patients with asthma is reduced markedly but it is not known whether this can also lead to an .
