Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells. | Respiratory Research BioMed Central Open Access Cryptococcus neoformans induces IL-8 secretion and CXCLI expression by human bronchial epithelial cells Loic Guillot1 Scott F Carroll1 2 Mohamed Badawy4 and Salman T Qureshi 1 3 Address 1McGill Centre for the Study of Host Resistance Room L11-403 1650 Cedar Avenue Montreal QC H3G 1A4 Canada 2Department of Human Genetics McGill University Montreal QC Canada 3Department of Medicine McGill University Montreal QC Canada and 4Faculty of Medicine Université de Montreal Montreal QC Canada Email Loic Guillot - Scott F Carroll - Mohamed Badawy - md_badawy@ Salman T Qureshi - Corresponding author Published 22 January 2008 Received 2 June 2007 Respiratory Research 2008 9 9 doi 1465-9921-9-9 Accepted 22 January 2008 This article is available from http content 9 1 9 2008 Guillot et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Cryptococcus neoformans C. neoformans is a globally distributed fungal pathogen with the potential to cause serious disease particularly among immune compromised hosts. Exposure to this organism is believed to occur by inhalation and may result in pneumonia and or disseminated infection of the brain as well as other organs. Little is known about the role of airway epithelial cells in cryptococcal recognition or their ability to induce an inflammatory response. Methods Immortalized BEAS-2B bronchial epithelial cells and primary normal human bronchial epithelium NHBE were stimulated in vitro with encapsulated or acapsular C. neoformans cultivated at room temperature or 37 C. Activation of bronchial epithelial cells was .