Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Open Access Long-term clearance from small airways in subjects with ciliary dysfunction. | Respiratory Research BioMed Central Research Open Access Long-term clearance from small airways in subjects with ciliary dysfunction Maria Lindstrom 1 2 Rolf Falk4 Lena Hjelte2 Klas Philipson3 and Magnus Svartengren1 Address 1Division of Occupational Medicine Department of Public Health Science Karolinska Institutet Stockholm Sweden 2Stockholm CF center Department of Paediatrics Karolinska Institutet Karolinska University Hospital Huddinge Stockholm Sweden 3Division of Inhalation Toxicology Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden and 4Swedish Radiation Protection Authority SSI Stockholm Sweden Email Maria Lindstrom - Rolf Falk - Lena Hjelte - Klas Philipson - Magnus Svartengren - Corresponding author Published 20 May 2006 Received 18 December 2005 Respiratory Research 2006 7 79 doi 1465-9921 -7-79 Accepted 20 May 2006 This article is available from http c0ntent 7 l 79 2006 Lindstrom et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The objective of this study was to investigate if long-term clearance from small airways is dependent on normal ciliary function. Six young adults with primary ciliary dyskinesia PCD inhaled 111 Indium labelled Teflon particles of pm geometric and pm aerodynamic diameter with an extremely slow inhalation flow L s. The inhalation method deposits particles mainly in the small conducting airways. Lung retention was measured immediately after inhalation and at four occasions up to 21 days after inhalation. Results were compared with data from ten healthy controls. For additional .
