Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells. | Respiratory Research BioMed Central Research Laminin-332 alters connexin profile dye coupling and intercellular Ca2 waves in ciliated tracheal epithelial cells Brant E Isakson41 2 Colin E Olsent3 and Scott Boitano 3 4 Open Access Address Department of Molecular Physiology and Biological Physics University of Virginia School of Medicine University of Virginia Charlottesville Virginia 22908 USA 2Robert M. Berne Cardiovascular Research Center University of Virginia School of Medicine University of Virginia Charlottesville Virginia 22908 USA 3Arizona Respiratory Center Arizona Health Sciences Center University of Arizona Tucson Arizona 85724 USA and 4Department of Physiology Arizona Health Sciences Center University of Arizona Tucson Arizona 85724 USA Email Brant E Isakson - bei6n@ Colin E Olsen - colsen@ Scott Boitano - sboitano@ Corresponding author tEqual contributors Published 02 August 2006 Received 24 January 2006 Respiratory Research 2006 7 105 doi 1465-9921-7-105 Accepted 02 August 2006 This article is available from http content 7 1 105 2006 Isakson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Tracheal epithelial cells are anchored to a dynamic basement membrane that contains a variety of extracellular matrix proteins including collagens and laminins. During development wound repair and disease of the airway epithelium significant changes in extracellular matrix proteins may directly affect cell migration differentiation and events mediated by intercellular communication. We hypothesized that alterations in cell matrix specifically
