Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation. | Respiratory Research BioMed Central Research Open Access Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation Clarisse Vandebrouck 1 Patricia Melin1 Caroline Norez1 Renaud Robert1 Christelle Guibert2 Yvette Mettey1 and Frédéric Becq1 Address 1Institut de Physiologie et Biologie Cellulaires CNRS UMR 6187 Université de Poitiers 40 Avenue du Recteur Pineau 86022 Poitiers Cedex France and 2Laboratoire de Physiologie Cellulaire Respiratoire INSERM 0356 Université Victor Segalen Bordeaux2 146 rue Léo Saignat 33076 Bordeaux Cedex France Email Clarisse Vandebrouck - Patricia Melin - Caroline Norez - cnorez@ Renaud Robert - renaud_robert7@ Christelle Guibert - Yvette Mettey- Frédéric Becq - Corresponding author Published 28 August 2006 Received 27 June 2006 Respiratory Research 2006 7 113 doi 1465-9921-7-113 Accepted 28 August 2006 This article is available from http content 7 1 1 13 2006 Vandebrouck et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The airway functions are profoundly affected in many diseases including asthma chronic obstructive pulmonary disease COPD and cystic fibrosis CF . CF the most common lethal autosomal recessive genetic disease is caused by mutations of the CFTR gene which normally encodes a multifunctional and integral membrane protein the CF transmembrane conductance regulator CFTR expressed in airway epithelial cells. Methods To demonstrate that CFTR is also expressed in tracheal smooth muscle cells
