Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Systematic review: The relation between nutrition and nosocomial pneumonia: randomized trials in critically ill patients. | Cook et al. Critical Care 1997 1 3 http c CRITICAL CARE RESEARCH Open Access Systematic review The relation between nutrition and nosocomial pneumonia randomized trials in critically ill patients Deborah Cook1 Bernard De Jonghe2 Daren Heyland3 Abstract Objective To review the effect of enteral nutrition on nosocomial pneumonia in critically ill patients as summarized in randomized clinical trials. Study identification and selection Studies were identified through MEDLINE SCISEARCH EMBASE the Cochrane Library bibliographies of primary and review articles and personal files. Through duplicate independent review we selected randomized trials evaluating approaches to nutrition and their relation to nosocomial pneumonia. Data abstraction In duplicate independently we abstracted key data on the design features population intervention and outcomes of the studies. Results We identified four trials of enteral vs total parenteral nutrition one trial of early enteral nutrition vs delayed enteral nutrition one trial of gastric vs jejunal tube feeding one trial of intermittent vs continuous enteral feeding and three trials evaluating different enteral feeding formulae. Sample sizes were small pneumonia definitions were variable and blinded outcome assessment was infrequent. Randomized trial evidence is insufficient to draw conclusions about the relation between enteral nutrition and nosocomial pneumonia. Conclusions Nutritional interventions in critically ill patients appear to have a modest and inconsistent effect on nosocomial pneumonia. This body of evidence neither supports nor refutes the gastropulmonary route of infection. enteral nutrition nosocomial pneumonia parenteral nutrition prevention ventilator-associated pneumonia Introduction Nosocomial pneumonia is an important cause of morbidity and mortality in hospitalized patients. Diagnosis and treatment continues to challenge clinicians and stimulate investigators. Prevention of this serious infection has .
