Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway. | BioMed Central Respiratory Research Research Open Access The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness a phase 3 comparison study with hypertonic saline John D Brannan1 Sandra D Anderson 1 Clare P Perry1 Ruth Freed-Martens1 Anna R Lassig2 Brett Charlton2 and the Aridol Study Group Address Department of Respiratory Medicine 11 West Royal Prince Alfred Hospital Missenden Road Camperdown NSW 2050 Australia and 2Pharmaxis Ltd. Unit 2 10 Rodborough Rd Frenchs Forest NSW 2086 Australia Email John D Brannan - johnb@ Sandra D Anderson - sandya@ Clare P Perry - clarep@ Ruth Freed-Martens - ruthm@ Anna R Lassig - Brett Charlton - the Aridol Study Group - ruthm@ Corresponding author Published 09 December 2005 Received 10 August 2005 Accepted 09 December 2005 Respiratory Research 2005 6 144 doi 86 1465-9921-6-144 This article is available from http content 6 1 144 2005 Brannan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Inhaled mannitol is a new bronchial provocation test BPT developed to improve portability and standardisation of osmotic challenge testing. Osmotic challenge tests have an advantage over the traditional methods of measuring airway hyperresponsiveness using methacholine as they demonstrate higher specificity to identify asthma and thus the need for treatment with inhaled corticosteroids ICS . The safety and the efficacy of mannitol M as a BPT to measure airway hyperresponsiveness were compared to hypertonic saline HS in people both with and without
