Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: World Congress on Lung Health and 10th ERS Annual . | http content 1 3 178 Meeting report World Congress on Lung Health and 10th ERS Annual Congress 30 August-3 September 2000 Florence Italy Pieter S Hiemstra Department of Pulmonology Leiden University Medical Center Leiden The Netherlands Received 9 October 2000 Accepted 19 October 2000 Published 6 November 2000 Respir Res 2000 1 178-179 Current Science Ltd Print ISSN 1465-9921 Online ISSN 1465-993X Pathogenesis of chronic obstructive pulmonary disease COPD The World Congress on Lung Health and 10th ERS Annual Congress brought together a wide range of scientists involved in studies on the pathogenesis of COPD. The research that was presented in various oral and poster presentations included a variety of approaches including cell biology studies analysis of lung tissue and studies of exhaled breath. The following report describes a selection of new developments related to research on the pathogenesis of COPD that were presented during the Florence meeting. Oxidative stress in COPD Whereas it is evident that cigarette smoke exposure results in oxidative stress it is also clear that the inflammatory process observed in patients with COPD asthma or cystic fibrosis for example results in disturbance of the oxidant-antioxidant balance. Several presentations focused on the alterations in cellular functioning that results from oxidative stress the body s antioxidant systems and methods to detect oxidative stress in tissue and exhaled breath. From presentations of Barnes and coworkers London UK and other research groups it is clear that the analysis of exhaled breath condensate might form an attractive non-invasive method for studying oxidative stress. However it is also evident that many methodological issues still remain to be resolved before highly reproducible methods can be introduced. After the reports of some years ago on increased levels of hydrogen peroxide in exhaled breath condensate of patients with COPD other markers of oxidative stress .
