Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Biphasic positive airway pressure ventilation (PeV+) in children. | Available online http content 5 3 174 Primary research Biphasic positive airway pressure ventilation PeV in children Anneke S Jaarsma Hennie Knoester Frank van Rooyen and Albert P Bos University Hospital Groningen Groningen The Netherlands Drager Lubeck Germany Correspondence . Jaarsma MD Department of Pediatrics University Hospital Groningen PO Box 30 001 9700 RB Groningen The Netherlands. Tel 31 503614215 fax 31 503614235 e-mail Received 6 February 2000 Revisions requested 8 August 2000 Revisions received 11 April 2001 Accepted 16 April 2001 Published 2 May 2001 Critical Care 2001 5 174-177 2001 Author et al licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Background Biphasic positive airway pressure BIPAP also known as PeV is a mode of ventilation with cycling variations between two continuous positive airway pressure levels. In adults this mode of ventilation is effective and is being accepted with a decrease in need for sedatives because of the ability to breathe spontaneously during the entire breathing cycle. We studied the use of BIPAP in infants and children. Methods We randomized 18 patients with respiratory failure for ventilation with either BIPAP n 11 or assisted spontaneous breathing ASB n 7 on Evita 4. Lorazepam and if necessary morphine were used as sedatives and adjusted in accordance with the Comfort scale. We compared number of randomized mode failure duration and complications of ventilation and number and dosages of sedatives administered. Results No differences in patient characteristics ventilatory parameters complications of ventilation or use of sedatives were noted. Ten out of eleven patients that we intended to ventilate with BIPAP were successfully ventilated with BIPAP. Four out of seven patients that we intended to ventilate with ASB could not be ventilated adequately with ASB but were successfully crossed over to BIPAP without the need for further sedatives. .
