Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Preoperative prediction of pediatric patients with effusions and edema following cardiopulmonary bypass surgery by serological and routine laboratory data. | Critical Care June 2002 Vol 6 No 3 Bocsi et al. Research Preoperative prediction of pediatric patients with effusions and edema following cardiopulmonary bypass surgery by serological and routine laboratory data Jozsef Bocsi1 Jorg Hambsch2 Pavel Osmancik3 Peter Schneider4 Gunter Valet5 and Attila Tárnok6 1 Director Flow Cytometry Unit 1st Department of Pathology Semmelweis University Budapest Hungary 2Assistant Medical Director Pediatric Cardiology Heart Center Leipzig GmbH University of Leipzig Germany 3Assistant Cardiologist Cardiac Center University Hospital Kralovske Vinohrady Charles University Prague Czech Republic 4Director Pediatric Cardiology Heart Center Leipzig GmbH University of Leipzig Germany 5Head Cell Biochemistry Group Max-Planck-Institute for Biochemistry Martinsried Munich Germany 6Head Research Facility Pediatric Cardiology Heart Center Leipzig GmbH University of Leipzig Germany Correspondence Attila Tárnok tarnok@ Received 19 February 2002 Accepted 22 February 2002 Published 8 April 2002 Critical Care 2002 6 226-233 2002 Bocsi et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Aim Postoperative effusions and edema and capillary leak syndrome in children after cardiac surgery with cardiopulmonary bypass constitute considerable clinical problems. Overshooting immune response is held to be the cause. In a prospective study we investigated whether preoperative immune status differences exist in patients at risk for postsurgical effusions and edema and to what extent these differences permit prediction of the postoperative outcome. Methods One-day preoperative serum levels of immunoglobulins complement cytokines and chemokines soluble adhesion molecules and receptors as well as clinical chemistry parameters such as differential counts creatinine blood coagulation status altogether 56 parameters were analyzed in peripheral blood samples of 75 children aged 3-18 years undergoing cardiopulmonary