Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Global expression profiling of theophylline response genes in macrophages: evidence of airway anti-inflammatory regulation. | Respiratory Research BioMed Central Research Open Access Global expression profiling of theophylline response genes in macrophages evidence of airway anti-inflammatory regulation Pei-Li Yao11 2 Meng-Feng Tsai11 2 Yi-Chen Lin1 2 Chien-Hsun Wang2 3 Wei-Yu Liao1 Jeremy JW Chen 2 3 and Pan-Chyr Yang 1 2 Address Department of Internal Medicine National Taiwan University Hospital No. 7 Chung-Shan South Rd. Taipei 100 Taiwan 2NTU Center for Genomic Medicine National Taiwan University College of Medicine Taipei 100 Taiwan and institutes of Biomedical Sciences and Molecular Biology National Chung-Hsing University No. 250 Kuo-Kuang Rd. Taichung 40227 Taiwan Email Pei-Li Yao - dalen@ Meng-Feng Tsai - tsai@ Yi-Chen Lin - vance@ Chien-Hsun Wang - topo@cm1 . Wei-Yu Liao - daphyu@ Jeremy JW Chen - jwchen@ Pan-Chyr Yang - pcyang@ Corresponding authors fEqual contributors Published 08 August 2005 Received 08 April 2005 Respiratory Research 2005 6 89 doi 1465-9921 -6-89 Accepted 08 August 2005 This article is available from http content 6 1 89 2005 Yao et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Theophylline has been used widely as a bronchodilator for the treatment of bronchial asthma and has been suggested to modulate immune response. While the importance of macrophages in asthma has been reappraised and emphasized their significance has not been well investigated. We conducted a genome-wide profiling of the gene expressions of macrophages in response to theophylline. Methods Microarray technology was used to profile the gene expression patterns of .
