Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Impact of salinomycin on the intestinal microflora of broiler chickens. | Acta Veterinaria Scandinavica BioMed Central Research Open Access Impact of salinomycin on the intestinal microflora of broiler chickens Charlotte H Johansen1 Lotte Bjerrum 1 and Karl Pedersen2 Address National Veterinary Institute Technical University of Denmark Hang0vej 2 DK-8200 Aarhus N Denmark and 2Department of Veterinary Pathobiology Faculty of Life Sciences University of Copenhagen Stigb0jlen 7 1870 Frederiksberg C Denmark Email Charlotte H Johansen - cjo@ Lotte Bjerrum - lob@ Karl Pedersen - kape@ Corresponding author Published 26 October 2007 Received 26 June 2007 Acta Veterinaria Scandinavica 2007 49 30 doi 1751-0147-49-30 Accepted 26 October 2007 This article is available from http content 49 1 30 2007 Johansen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The ionophoric coccidiostat salinomycin is widely used in chicken feed. In the near future the use of ionophore coccidiostats may be banned as has been the case for other antimicrobial growth promoters. This study was conducted to examine the effect of salinomycin on Campylobacter jejuni infection and on the composition of the caecal microflora in broiler chickens. Methods An experimental infection study was carried out in isolators and the intestinal microflora was analyzed using quantitative cultivation denaturant gradient gel electrophoresis DGGE cloning and sequencing. Results We found no effect of salinomycin on but salinomycin significantly affected the composition of the microflora. In addition salinomycin significantly reduced the prevalence of Clostridium perfringens and we observed a significant increase 62 in the mean body weight of salinomycin treated .
