Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Pyelonephritis in slaughter pigs and sows: Morphological characterization and aspects of pathogenesis and aetiology. | Isling et al. Acta Veterinaria Scandinavica 2010 52 48 http content 52 1 48 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Pyelonephritis in slaughter pigs and sows Morphological characterization and aspects of pathogenesis and aetiology Louise K Isling1 Bent Aaltek1 Malene Schroder2 Páll S Leifsson1 Abstract Background Pyelonephritis is a serious disease in pig production that needs to be further studied. The purpose of this study was to describe the morphology investigate the pathogenesis and evaluate the aetiological role of Escherichia coli in pyelonephritis in slaughtered pigs by concurrent bacteriological gross and histopathological examinations. Methods From Danish abattoirs kidneys and corresponding lymph nodes from 22 slaughtered finishing pigs and 26 slaughtered sows with pyelonephritis were collected and evaluated by bacteriology and pathology. Based on gross lesions each kidney lesion was grouped as acute chronic chronic active or normal and their histological inflammatory stage was determined as normal 0 acute 1 sub-acute 2 chronic active 3 or chronic 4 . Immunohistochemical identification of neutrophils macrophages T-lymphocytes B-lymphocytes plasma cells E. coli and Tamm-Horsfall protein THP in renal sections was performed. The number of E. coli and the proportion of immunohistochemically visualized leukocytes out of the total number of infiltrating leukocytes were scored semi-quantitatively. Results Lesions in finishing pigs and sows were similar. Macroscopically multiple unevenly distributed foci of inflammation mostly affecting the renal poles were observed. Histologically tubulointerstitial infiltration with neutrophils and mononuclear cells and tubular destruction was the main findings. The significant highest scores of L1 antigen neutrophils were in inflammatory stage 1 while the significant highest scores of CD79acy B-lymphocytes IgG and IgA plasma cells were in stage 3 or 4. Neutrophils were the dominant leukocytes
