Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Evaluation of the Swedish breeding program for cavalier King Charles spaniels. | Lundin and Kvart Acta Veterinaria Scandinavica 2010 52 54 http content 52 1 54 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Evaluation of the Swedish breeding program for cavalier King Charles spaniels Tobias Lundin1 Clarence Kvart2 Abstract A breeding program with the aim of reducing the prevalence of mitral regurgitation MR caused by myxomatous mitral valve disease MMVD in Cavalier King Charles Spaniels CKCS is currently ongoing in Sweden. In this investigation 353 CKCS were selected as a sample of the population and 150 were examined by auscultation for heart murmurs when they reached the age of six years in 2007 and 2009. The aim with this investigation was to study the prevalence of heart murmurs in six-year-old CKCS and to estimate if prevalence has decreased since the breeding program was introduced 2001. The effect of the breeding program was evaluated by comparing the prevalence of heart murmurs in the two groups. In 2007 the prevalence of heart murmurs was 52 50 for females and 54 for males and in 2009 the prevalence was 55 44 for females and 67 for males . No significant difference was found in the prevalence of heart murmurs between 2007 and 2009 P . For all six-year-old CKCS the prevalence of heart murmur was 53 females 46 and males 61 which is higher than previous Swedish investigations. Background Mitral regurgitation MR secondary to myxomatous mitral valve disease MMVD is the most common cardiac disorder in dogs and is usually caused by progressive degeneration of the atrioventricular valves. Degeneration of the atrioventricular valves renders the leaflets thicker and irregular leading to insufficient coaptation of the leaflets and regurgitation of blood with accompanying enlargement of the atria and ventricles. These pathological changes are associated with a characteristic systolic heart murmur when the valves become incompetent and blood is ejected back into the atrium during systole. The mitral valve alone or .
