Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. | Ruprechter et al. Acta Veterinaria Scandinavica 2011 53 35 http content 53 1 35 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions effect of polymorphisms in somatotropic axis genes 1 1 2 1 1 Gretel Ruprechter Mariana Carriquiry Juan Manuel Ramos Isabel Pereira and Meikle Ana Abstract Background The present study hypothesized that GH-AluI and IGF-I-SnabI polymorphisms do change the metabolic endocrine profiles in Holstein cows during the transition period which in turn are associated with productive and reproductive parameters. Methods Holstein cows Farm 1 primiparous cows n 110 and Farm 2 multiparous cows n 76 under grazing conditions were selected and GH and IGF-I genotypes were determined. Blood samples for metabolic endocrine determinations were taken during the transition period and early lactation in both farms. Data was analyzed by farm using a repeated measures analyses including GH and IGF-I genotypes days and interactions as fixed effects sire and cow as random effects and calving date as covariate. Results and Discussion Frequencies of GH and IGF-I alleles were L V and A B respectively. The GH genotype was not associated with productive or reproductive variables but interaction with days affected FCM yield in multiparous farm 2 cows LL yielded more than LV cows in early lactation. The GH genotype affected NEFA and IGF-I concentrations in farm 1 LV had higher NEFA and lower IGF-I than LL cows suggesting a better energy status of LL cows. There was no effect of IGF-I genotype on productive variables but a trend was found for FCM in farm 2 AB cows yielded more than AA cows . IGF-I genotype affected calving first service interval in farm 1 and the interaction with days tended to affect FCM yield AB cows had a shorter interval and yielded more FCM than BB cows . IGF-I genotype affected BHB NEFA and insulin .