Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Evaluation of LHP® (1% hydrogen peroxide) cream versus petrolatum and untreated controls in open wounds in healthy horses: a randomized, blinded control study. | Tóth et al. Acta Veterinaria Scandinavian 2011 53 45 http content 53 1 45 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Evaluation of LHP 1 hydrogen peroxide cream versus petrolatum and untreated controls in open wounds in healthy horses a randomized blinded control study Tamás Tóth1 Hans Brostrom2 Viveca Baverud3 Ulf Emanuelson2 Elisabeth Bagge3 Tommy Karlsson2 and Kerstin Bergvall2 Abstract Background Treatment and protection of wounds in horses can be challenging protecting bandages may be difficult to apply on the proximal extremities and the body. Unprotected wounds carry an increased risk of bacterial contamination and subsequent infection which can lead to delayed wound healing. Topical treatment with antimicrobials is one possibility to prevent bacterial colonization or infection but the frequent use of antimicrobials ultimately leads to development of bacterial resistance which is an increasing concern in both human and veterinary medicine. Methods Standardized wounds were created in 10 Standardbred mares. Three wounds were made in each horse. Two wounds were randomly treated with LHP or petrolatum and the third wound served as untreated control. All wounds were assessed daily until complete epithelization. Protocol data were recorded on day 2 6 11 16 21 and 28. Data included clinical scores for inflammation and healing photoplanimetry for calculating wound areas and swab cytology to assess bacterial colonization and inflammation. Bacterial cultures were obtained on day 2 6 and 16. Results Mean time to complete healing for LHP treated wounds was 32 days 95 CI . Mean time to complete healing for petrolatum and untreated control wounds were days 95 CI and days 95 CI respectively. Wound healing occurred significantly faster in LHP wounds compared to both petrolatum p and untreated controls p . There was no significant difference in time for healing between petrolatum and .
