Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Clinical review: High-frequency oscillatory ventilation in adults — a review of the literature and practical applications. | Available online http content 7 5 385 Review Clinical review High-frequency oscillatory ventilation in adults -a review of the literature and practical applications Frank V Ritacca1 and Thomas E Stewart2 3 1 Clinical Fellow Division of Respirology and Interdepartmental Division of Critical Care Medicine University of Toronto Toronto Ontario Canada 2Associate Professor Division of Respirology and Interdepartmental Division of Critical Care Medicine University of Toronto Toronto Ontario Canada 3Director Critical Care Unit Mount Sinai Hospital and University Health Network University of Toronto Toronto Ontario Canada Correspondence Thomas E Stewart tstewart@ Published online 17 April 2003 Critical Care 2003 7 385-390 DOI cc2182 This article is online at http content 7 5 385 2003 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract It has recently been shown that strategies aimed at preventing ventilator-induced lung injury such as ventilating with low tidal volumes can reduce mortality in patients with acute respiratory distress syndrome ARDS . High-frequency oscillatory ventilation HFOV seems ideally suited as a lung-protective strategy for these patients. HFOV provides both active inspiration and expiration at frequencies generally between 3 and 10 Hz in adults. The amount of gas that enters and exits the lung with each oscillation is frequently below the anatomic dead space. Despite this gas exchange occurs and potential adverse effects of conventional ventilation such as overdistension and the repetitive opening and closing of collapsed lung units are arguably mitigated. Although many investigators have studied the merits of HFOV in neonates and in pediatric populations evidence for its use in adults with ARDS is limited. A recent multicenter randomized controlled trial has shown that HFOV when used early in ARDS is at least equivalent to conventional ventilation and may have beneficial effects on .
