Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomized, double-blind controlled trial [ISRCTN43755713]. | Available online http content 8 1 R1 Research Open Access Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit a randomized double-blind controlled trial ISRCTN43755713 Bernd Muellejans1 Angel Lopez2 Michael H Cross3 César Bonome4 Lachlan Morrison5 and Andrew JT Kirkham6 1 Director of Anaesthesiology Intensive Care Medicine Klinikum Karlsburg Herz-und Diabeteszentrum Mecklenburg-Vorpommern Klinik fur Anaesthesiologie und Intensivmedizin Karlsburg Germany 2Consultant Anaesthesiologist Servicio de Medicina Intensiva Hospital Universitario Infanta Cristina Badajoz Spain 3Consultant Anaesthetist Department of Anaesthesia Leeds General Infirmary Leeds UK 4Attending Staff Department of Anaesthesiology Hospital Juan Canalejo Servicio de Anestesiologia y Reanimación La Coruna Spain 5Consultant in Anaesthetics and Intensive Care Department of Anaesthesia St. John s Hospital Livingston UK 6Global Study Manager GlaxoSmithKline Research and Development Greenford UK Correspondence Bernd Muellejans Received 2 October 2003 Accepted 16 October 2003 Published 20 November 2003 Critical Care 2004 8 R1-R11 DOI cc2398 This article is online at http content 8 1 R1 2004 Muellejans et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X . This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Introduction This double-blind randomized multicentre study was conducted to compare the efficacy and safety of remifentanil and fentanyl for intensive care unit ICU sedation and analgesia. Methods Intubated cardiac general postsurgical or medical patients aged 18 years who were mechanically ventilated for 12-72 hours received remifentanil 9 ựg kg per hour n 77 or fentanyl ựg kg per hour n 75 . Initial opioid .
