Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Science review: Quantitative acid–base physiology using the Stewart model. | Critical Care December 2004 Vol 8 No 6 Wooten Review Science review Quantitative acid-base physiology using the Stewart model E Wrenn Wooten Attending Physician Radiology Associates PA Little Rock Arkansas USA Corresponding author E Wrenn Wooten wootenew@ Published online 2 July 2004 This article is online at http content 8 6 448 2004 BioMed Central Ltd Critical Care 2004 8 448-452 DOI cc2910 Abstract There has been renewed interest in quantifying acid-base disorders in the intensive care unit. One of the methods that has become increasingly used to calculate acid-base balance is the Stewart model. This model is briefly discussed in terms of its origin its relationship to other methods such as the base excess approach and the information it provides for the assessment and treatment of acid-base disorders in critically ill patients. Keywords acid-base base excess Stewart model Introduction Acid-base derangements are commonly encountered in the critical care unit 1 and there is renewed interest in the precise description of these disorders in critically ill patients 2-5 . This new interest has led to a renovation of the quantitative assessment of physiological acid-base balance with increasing use of the Stewart model strong ion difference SID theory to calculate acid-base balance in the critically ill 2 3 6 7 . This method is discussed particularly as it pertains to the metabolic component of acid-base derangements as one of several approaches that may be used in the intensive care unit for quantitative evaluation. As with any mathematical model a basic understanding of its principles is useful for proper application and interpretation. Stewart model All equilibrium models of acid-base balance utilize the same basic concept. Under the assumption of equilibrium or a steady-state approximation to equilibrium some property of the system . proton number proton binding sites or charge among other possible properties is enumerated from the .
