Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]. | Available online http content 8 6 R443 Open Access Research G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children - safety and cost effectiveness of a new laboratory prediction model study protocol of a randomized controlled trial ISRCTN91123847 Thomas Horisberger1 Stephan Harbarth2 David Nadal3 Oskar Baenziger4 and Joachim E Fischer5 1Research Fellow Department of Neonatology and Intensive Care University Children s Hospital Zurich Switzerland 2Scientific Consultant Infection Control Program Geneva University Hospitals Geneva Switzerland 3Head Division of Infectious Diseases University Childrens s Hospital Zurich Zurich Switzerland 4Head Department of Neonatology and Intensive Care University Children s Hospital Zurich Switzerland 5Consultant Department of Neonatology and Intensive Care University Children s Hospital Zurich Switzerland Corresponding author Joachim E Fischer Received 26 August 2004 Critical Care 2004 8 R443-R450 DOI cc2971 Accepted 9 September 2004 This article is online at http content 8 6 R443 Published 19 October 2004 2004 Horisberger et al licensee BioMed Central Ltd. This is an open-access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Bacterial infection represents a serious risk in neonates and critically ill paediatric patients. Current clinical practice is characterized by frequent antibiotic treatment despite low incidence of true infection. However some patients escape early diagnosis and progress to septic shock. Many new markers including cytokines have been suggested to improve decision making but the clinical efficacy of these techniques remains uncertain. Therefore we will test the clinical efficacy of a previously validated .
