Báo cáo y học: "Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis. | Available online http content 9 1 R53 Re search Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis Argyris Michalopoulos1 Sofia K Kasiakou2 Zefi Mastora3 Kostas Rellos4 Anastasios M Kapaskelis5 and Matthew E Falagas6 Director Intensive Care Unit Henry Dunant Hospital Athens Greece 2Research Fellow Alfa HealthCare Athens Greece 3Attending Physician Intensive Care Unit Henry Dunant Hospital Athens Greece 4Associate Director Intensive Care Unit Henry Dunant Hospital Athens Greece 5Attending Physician Alfa HealthCare and Department of Medicine Henry Dunant Hospital Athens Greece 6Adjunct Assistant Professor of Medicine Tufts University School of Medicine Boston Massachusetts USA and Director Infectious Diseases Clinic Department of Medicine Henry Dunant Hospital Athens Greece Open Access Corresponding author Matthew E Falagas Received 6 August 2004 Revisions requested 17 September 2004 Revisions received 24 September 2004 Accepted 18 November 2004 Published 6 January 2005 Critical Care 2005 9 R53-R59 DOI cc3020 This article is online at http content 9 1 R53 2004 Michalopoulos et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is cited. Abstract Introduction The clinical and economic consequences of the emergence of multidrug-resistant Gramnegative bacteria in the intensive care unit ICU setting combined with the high mortality rate among patients with nosocomial pneumonia have stimulated a search for alternative therapeutic options to treat such infections. The use of adjunctive therapy with aerosolized colistin represents one of these. There is extensive experience with use of aerosolized

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