Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Pulmonary capillary pressure in pulmonary hypertension. | Available online http content 9 2 R132 Research Pulmonary capillary pressure in pulmonary hypertension Rogerio Souza Marcelo Britto Passos Amato Sergio Eduardo Demarzo Daniel Deheinzelin Carmen Silvia Valente Barbas Guilherme Paula Pinto Schettino and Carlos Roberto Ribeiro Carvalho Open Access Pulmonary Division Respiratory ICU - Heart Institute InCor University of São Paulo Medical School São Paulo Brazil Corresponding author Rogerio Souza rgrsz@ Received 2 September 2004 Revisions requested 2 November 2004 Revisions received 22 November 2004 Accepted 7 December 2004 Published 11 February 2005 Critical Care 2005 9 R132-R138 DOI cc3038 This article is online at http content 9 2 R132 2005 Souza et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is cited. Abstract Introduction Pulmonary capillary pressure PCP together with the time constants of the various vascular compartments define the dynamics of the pulmonary vascular system. Our objective in the present study was to estimate PCPs and time constants of the vascular system in patients with idiopathic pulmonary arterial hypertension IPAH and compare them with these measures in patients with acute respiratory distress syndrome ARDS . Methods We conducted the study in two groups of patients with pulmonary hypertension 12 patients with IPAH and 11 with ARDS. Four methods were used to estimate the PCP based on monoexponential and biexponential fitting of pulmonary artery pressure decay curves. Results PCPs in the IPAH group were considerably greater than those in the ARDS group. The PCPs measured using the four methods also differed significantly suggesting that each method measures the pressure at a different site in the pulmonary circulation. The
